Certificates of Analysis

Reversed-phase HPLC (High-Performance Liquid Chromatography) separates compounds by hydrophobicity and measures purity as a percentage of the total integrated peak area. LC-MS (Liquid Chromatography–Mass Spectrometry) adds molecular weight confirmation, verifying that the detected compound has the correct sequence identity — not just that a pure compound is present. Using both methods together is the analytical gold standard for research-grade peptides.

Yes. Every compound listed in our product catalog is assigned a batch-matched COA from Freedom Diagnostic before it is made available for wholesale purchase. We do not offer products that have not passed independent purity verification. The COA document ships with your order and is also available for pre-order review on request.

Purity describes what percentage of the material is the intended peptide compound versus impurities. Potency describes how biologically active that compound is in a specific assay context. A peptide can be ≥99% pure but still exhibit variable potency depending on reconstitution protocol, storage conditions, and the research application. 99 Purity Wholesale guarantees purity as verified by analytical instrumentation — potency for a specific research endpoint is outside the scope of COA documentation.

Our compounds are synthesized in a U.S.-based facility using solid-phase peptide synthesis (SPPS). Independent third-party verification through Freedom Diagnostic serves as our primary quality assurance mechanism. We do not hold an FDA drug manufacturing license, as our products are supplied strictly for licensed research use — not for human administration. We apply rigorous synthesis and handling standards consistent with research-grade supply.

Any production lot that fails the ≥99% purity threshold in Freedom Diagnostic testing is rejected and not released into the wholesale catalog. We do not discount or remarket failing batches under any circumstances. Only lots with a passing COA are made available for order. This no-exceptions rejection policy is the foundation of our quality guarantee to wholesale accounts.

A COA reflects the purity of a batch at the time of testing and does not expire as a document — it is a permanent record tied to that lot number. However, actual compound integrity is affected by storage conditions over time. We recommend storing lyophilized peptides sealed at -20°C for long-term stability, retaining the COA as a reference document throughout your research project.

Yes. Prospective wholesale accounts can request sample COA documentation for any compound in our catalog prior to submitting an order. Contact our B2B team via WhatsApp or email at wholesale@99puritypeptides.com to request the batch documentation for your compound of interest.

Most overseas suppliers operate at 95%–98% purity standards, with COAs produced by in-house or affiliated labs — a fundamental conflict of interest. 99 Purity Wholesale uses exclusively independent third-party testing through Freedom Diagnostic, enforces a ≥99% minimum with no exceptions, and ships from within the U.S. with no customs exposure. See our full comparison table for a structured breakdown.

SPPS is the industry-standard method for manufacturing research peptides. Amino acids are assembled sequentially on a solid resin support, building the target peptide chain one residue at a time. This method allows precise control over sequence fidelity and minimizes the byproduct profile. The resulting crude peptide is then purified and submitted to Freedom Diagnostic for analytical verification before any batch is released to the wholesale catalog.