Dihexa Spray

Dihexa Spray is supplied as a pre-dissolved, sterile-filtered solution in amber glass bottles fitted with a metered atomizer, at 10 mg per unit. This compound is markedly more lipophilic than the peptides around it in this catalog, thanks to a six-carbon acyl chain at one end and a six-carbon amide linker at the other, so the formulation is built to hold it in solution and to limit adsorption onto container surfaces. Headspace is nitrogen-purged before capping, and no reconstitution is required.

Store Dihexa Spray refrigerated at 2°C to 8°C (36°F to 46°F), upright and protected from light, where sealed units remain within specification for up to 24 months. Once the atomizer is first actuated, use the unit within 30 days. Avoid unnecessary transfers between containers: lipophilic compounds adsorb onto plastic surfaces and each transfer quietly lowers the working concentration without any chemical degradation occurring. Avoid freeze-thaw cycling, which can cause the compound to come out of solution. Brief transit excursions to 15°C to 25°C (59°F to 77°F) are tolerated.

Dihexa is a small angiotensin IV-derived molecule built from two amino acids capped with a six-carbon acyl group and a six-carbon amide linker. The proposed mechanism is potentiation of hepatocyte growth factor signaling at the c-Met receptor tyrosine kinase, which would place it in a different mechanistic category from the receptor agonists elsewhere in this catalog. That said, the evidence base requires a clear caveat. The two papers that originally established the hepatocyte growth factor and c-Met mechanism were retracted by the publishing journal in 2025. McCoy and colleagues characterized the metabolically stabilized angiotensin IV analog series in work that has not been retracted, and Sun and colleagues later reported effects through PI3K and Akt signaling in a transgenic mouse model.

Yes. Qualified procurement partners can request alternative concentrations, non-standard bottle volumes, unlabeled or private-label presentation, or co-formulation with complementary cognitive research compounds such as Semax. Contact our corporate sales desk with your target concentration and unit count to scope the run.

Units ship in light-blocking, vacuum-sealed secondary packaging with temperature-stability buffers that hold the shipment inside the refrigerated range through transit. Amber primary containers and nitrogen-purged headspace protect the hydrophobic acyl chain against adsorption losses. We ship nationwide across all 50 US states and internationally via express couriers with discrete, border-optimized clearance and full delivery assurance.