Melanotan-1 Spray

Melanotan-1 Spray is supplied as a pre-dissolved, sterile-filtered solution in amber glass bottles fitted with a metered atomizer, at 10 mg per unit. Amber glass earns its place here: the tryptophan residue absorbs in the near-ultraviolet and photodegrades under ambient light, which is a genuine handling constraint for this sequence. Headspace is nitrogen-purged before capping, and no reconstitution step is required.

Store Melanotan-1 Spray refrigerated at 2°C to 8°C (36°F to 46°F), upright and protected from light, where sealed units remain within specification for up to 24 months. Once the atomizer is first actuated, use the unit within 30 days. Light protection is more than routine caution for this peptide, since tryptophan photodegradation proceeds even at room lighting levels. Avoid freeze-thaw cycling. Brief transit excursions to 15°C to 25°C (59°F to 77°F) are tolerated.

Melanotan-1, known in the literature as afamelanotide, is a 13-residue analog of alpha-melanocyte-stimulating hormone that acts as a selective agonist at the melanocortin-1 receptor on melanocytes. Receptor activation raises cAMP and activates protein kinase A, which phosphorylates CREB and drives expression of the transcription factor MITF. MITF in turn controls transcription of tyrosinase, the rate-limiting enzyme of eumelanin synthesis. Two engineered substitutions define the molecule: a norleucine replacing the oxidation-prone methionine at position four, and a D-phenylalanine at position seven that blocks enzymatic degradation and locks the bioactive conformation. Sawyer and colleagues reported the result as ultralong biological activity. Unlike Melanotan-2, a cyclic analog with broad activity across several melanocortin receptors, Melanotan-1 is the selective one.

Yes. Qualified procurement partners can request alternative concentrations, non-standard bottle volumes, unlabeled or private-label presentation, or co-formulation with complementary melanocortin research compounds such as Melanotan-2. Contact our corporate sales desk with your target concentration and unit count to scope the run.

Units ship in light-blocking, vacuum-sealed secondary packaging with temperature-stability buffers that hold the shipment inside the refrigerated range through transit. Amber primary containers and nitrogen-purged headspace protect the D-phenylalanine stereocentre and the tryptophan residue. We ship nationwide across all 50 US states and internationally via express couriers with discrete, border-optimized clearance and full delivery assurance.